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PNC27 Anticancer Peptide Manufacturer China High Quality Suppliers Factory
Buy PNC-27 anti-cancer peptides in 5MG and 10MG specifications. Leading China factory and suppliers providing high-precision HDM-2 targeting peptides for oncology research.
SupplierFuBai Peptidewww.glpfactory.com
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About this product
Product information from the supplier.
PNC-27 is a cutting-edge experimental anti-cancer peptide meticulously engineered for high-precision oncology research. By fusing the HDM-2-binding domain of the p53 protein with a specialized membrane-penetrating sequence, PNC-27 represents a significant leap in targeted therapeutic design, specifically developed to overcome the barriers of cellular entry while maintaining high binding affinity.
Designed for selective action, PNC-27 specifically identifies and binds to HDM-2 proteins expressed on the surface of tumor cells. Once attached, it triggers rapid cell membrane destruction and necrosis. This mechanism ensures a potent cytotoxic effect on malignant cells while remaining inert toward healthy, normal cells, thereby minimizing off-target toxicity in experimental models.
Detailed Parameters
| Product Name | PNC-27 | Product Category | Anti-cancer Peptide / Biopharmaceutical |
|---|---|---|---|
| Target Protein | HDM-2 (p53-binding domain) | Mechanism | Membrane Penetrating & Necrosis |
| Binding Site | Tumor Cell Surface | Active Component | p53-derived Binding Domain |
| Cellular Effect | Selective Membrane Destruction | Application | Experimental Cancer Research |
| Selectivity | Tumor-specific (Non-toxic to healthy cells) | Chemical Class | Synthetic Peptide |
Key Advantages
High Selectivity
Precisely targets HDM-2 proteins on tumor surfaces, ensuring healthy cells remain unaffected.
Rapid Necrosis
Induces swift cell membrane destruction, leading to efficient tumor cell necrosis.
Enhanced Penetration
Integrated membrane-penetrating sequence ensures optimal delivery to the target site.
p53 Domain Mimicry
Utilizes the biological precision of the p53 HDM-2 binding domain for superior affinity.
Low Toxicity
Designed to avoid non-specific interactions, reducing potential experimental side effects.
Research Grade
Manufactured under strict quality controls for consistent results in genetic engineering studies.
Product Gallery
Management Platforms
Peptide Synthesis Control
Automated synthesis platforms ensuring sequence accuracy and high purity levels.
Quality Assurance (QA)
Rigorous HPLC and Mass Spectrometry validation for every batch produced.
Cold Chain Logistics
Advanced temperature-controlled shipping to maintain peptide stability.
Batch Traceability
Full digital tracking from raw amino acid sourcing to final delivery.
Inventory Management
Real-time stock monitoring to ensure rapid fulfillment of research orders.
Regulatory Compliance
Adherence to international standards for biological drug manufacturing.
Investment Return Comparison
| Metric | Conventional Chemotherapy | PNC-27 Targeted Peptide |
|---|---|---|
| Cell Selectivity | Low (Systemic) | High (Tumor Specific) |
| Healthy Cell Damage | Significant | Minimal to None |
| Action Speed | Moderate | Rapid Necrosis |
| Target Accuracy | General Cytotoxic | HDM-2 Specific |
| Experimental Value | Baseline | High Innovation Potential |
Frequently Asked Questions
Q: What is the primary application of PNC-27 in bio-pharmaceutical manufacturing?
PNC-27 is primarily used in experimental oncology and genetic engineering research to study targeted cell necrosis and the inhibition of HDM-2 proteins in tumor cells.
Q: How does the membrane-penetrating sequence benefit the peptide's function?
The membrane-penetrating sequence allows the peptide to bypass the cellular lipid bilayer efficiently, ensuring the HDM-2-binding domain can interact with its target on the cell surface and induce necrosis.
Q: Does PNC-27 affect normal, non-cancerous cells?
No, PNC-27 is engineered for high selectivity. It specifically targets the HDM-2 proteins overexpressed on tumor cells, meaning healthy cells that lack these markers are typically unharmed.
Q: What quality standards are applied to the manufacturing of these vaccines and peptides?
Our manufacturing follows strict pharmaceutical-grade protocols, utilizing HPLC and mass spectrometry to ensure chemical purity and biological activity for research purposes.
Q: Can PNC-27 be customized for different research requirements?
Yes, we provide custom peptide synthesis services where the sequence or binding domains can be modified to meet specific experimental needs in genetic engineering.
Q: How should PNC-27 be stored to maintain its stability?
To preserve biological activity, it is recommended to store PNC-27 in a lyophilized state at -20°C or -80°C, away from light and moisture.
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