[His1, Lys6] – GHRP, GHRP- 6 CAS NO.87616-84-0
[His¹, Lys⁶]-GHRP, GHRP-6 (CAS No. 87616-84-0) is a synthetic hexapeptide with the molecular formula C₄₆H₅₆N₁₂O₆ and a molecular weight of 873.04g/mol. It is widely used in research for its potent growth hormone-releasing activity.
About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | [His¹, Lys⁶]-GHRP, GHRP-6 |
| CAS NO. | 87616-84-0 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C46H56N12O6 |
| Molecular Weight | 873.04g/mol |
| Amino Acid Sequence | His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂ |
| Purity (RP-HPLC) | ≥98.0% |
| Solubility | Soluble in water, physiological saline, and dilute acetic acid solution |
| Endotoxin | ≤1.0 EU/mg |
| Biological Activity | Synthetic hexapeptide and growth hormone secretagogue (GHS); stimulates GH release via ghrelin receptor (GHSR‑1a), used in research on growth, metabolism, and appetite regulation. |
| Storage Conditions | Store at –20°C, protected from light and moisture. For long-term storage, recommend –80°C. |
| Stock Location | Stock in USA |
| MOQ | 1mg |
1.MECHANISM OF ACTION
This peptide acts as a selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR-1a), stimulating the release of growth hormone from the pituitary gland. It bypasses the natural hypothalamic control, directly promoting GH secretion and influencing downstream metabolic and anabolic processes.
2.PRODUCT INDICATIONS
GHRP-6 is used in scientific studies related to growth disorders, muscle wasting, metabolism, appetite regulation, and tissue repair. It is also applied in research investigating age-related hormone decline, sports science, and the development of therapeutic strategies for catabolic conditions.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical and limited clinical studies indicate that GHRP-6 effectively increases serum growth hormone levels, promotes muscle growth, enhances wound healing, and improves metabolic parameters. Its potential benefits in treating growth hormone deficiency and sarcopenia are supported by experimental data, though broader clinical validation is ongoing.
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