Chemicals

Growth Hormone Releasing Factor, GRF, (1 – 40), human

Growth Hormone Releasing Factor, GRF, (1-40), human (CAS No. 83930-13-6) is a synthetic peptide with the molecular formula C194H317N61O63S and a molecular weight of 4547.2 g/mol. It is a potent endogenous hormone that stimulates the secretion of growth hormone (GH) and is w

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TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Growth Hormone Releasing Factor, GRF, (1-40), human
CAS NO.
87616-84-0
Appearance
White to off-white lyophilized powder
Molecular Formula
C194H317N61O63S
Molecular Weight
4544.12g/mol 
Amino Acid Sequence
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂ (human GRF₁‑₄₀)
Purity (RP-HPLC)
≥95.0% (customizable to ≥98.0%)
Solubility

Soluble in water, dilute acetic acid solution, and aqueous buffers (e.g., PBS)
Endotoxin≤1.0 EU/mg
Biological Activity
Potent stimulator of growth hormone (GH) secretion via binding to the GHRH receptor; used in endocrine research, growth studies, and diagnostic assays.
Storage Conditions
Store at –20°C, protected from light and moisture. For long-term storage, recommend –80°C.
Stock Location
Stock in USA
MOQ

10mg


1.MECHANISM OF ACTION

This peptide acts as a selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR-1a), stimulating the release of growth hormone from the pituitary gland. It bypasses the natural hypothalamic control, directly promoting GH secretion and influencing downstream metabolic and anabolic processes.


2.PRODUCT INDICATIONS

Growth Hormone Releasing Factor, GRF, (1-40), human is primarily applied in scientific studies on growth disorders, age-related GH decline, metabolic syndromes, and tissue regeneration. It is also used in diagnostic testing for pituitary function and in the development of GH-based therapeutic strategies.


3.CLINICAL EFFICACY OF PRODUCT

Preclinical and clinical studies have demonstrated that this peptide effectively elevates serum GH levels, promotes anabolic effects such as muscle growth and bone density improvement, and enhances metabolic parameters. Its role in the diagnosis and management of growth hormone deficiency underscores its relevance in both research and potential clinical applications.


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.