Chemicals

Histatin 3 (H3)

<p>Histatin 3 (H3) (CAS No. 135156-99-9) is a high‑purity, histidine‑rich bioactive peptide. The full product specifications, including molecular formula, molecular weight, amino acid sequence, purity, and solubility, are provided in the technical data sheet. This antimicrobial peptide is a key reagent for oral biology, dermatology, and infection research.</p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Histatin 3 (H3)
CAS NO.

Appearance
White to off-white lyophilized powder
Molecular Formula
C178H258N64O48
Amino Acid Sequence
DSHAKRHHGYKRKFHEKHHSHRGY (human Histatin 3 sequence)
Molecular Weight
4062.44g/mol 
Purity (RP-HPLC)
≥ 95.0%
Solubility

Soluble in water, dilute acetic acid, or PBS (pH 7.0‑7.4)

Endotoxin< 1.0 EU/mg
Biological Activity
Antimicrobial and wound‑healing peptide; exhibits antifungal, antibacterial, and immunomodulatory activities; used in oral biology, dermatology, and infection research.
Storage Conditions
Store at –20°C, protected from light and moisture. For long‑term storage, recommend –80°C.
Stock Location
Stock in USA
MOQ
1mg


1.MECHANISM OF ACTION

Histatin 3 (H3) exerts its antimicrobial activity by disrupting microbial membranes through electrostatic interactions and pore formation, leading to cell lysis and death. It also exhibits immunomodulatory functions, such as promoting wound healing and modulating inflammatory responses in host tissues.


2.PRODUCT INDICATIONS

This peptide is used in research focused on oral infections (e.g., dental caries, periodontitis), skin infections, wound healing, and antimicrobial drug development. It is also applied in studies of biofilm formation, host‑microbe interactions, and the design of peptide‑based therapeutic agents.


3.CLINICAL EFFICACY OF PRODUCT

Preclinical studies have demonstrated that Histatin 3 (H3) effectively reduces bacterial and fungal loads in oral and dermal infection models, accelerates wound closure, and enhances tissue repair. These findings support its potential as a lead compound for developing topical or oral formulations in clinical oral‑health and dermatological applications.


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.