LHRH-Ⅲ, lamprey CAS NO.147859-97-0

<p>LHRH-Ⅲ, lamprey is a high-purity synthetic decapeptide corresponding to the third isoform of lamprey gonadotropin-releasing hormone. This evolutionarily conserved neuropeptide plays a crucial role in regulating reproductive functions in jawless vertebrates, making it a valuable tool for comparative endocrinology, evolutionary biology, and neuroendocrine research. Manufactured under stringent quality controls with…

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	LHRH-Ⅲ, lamprey
CAS NO.	147859-97-0
Appearance	White to off-white lyophilized powder
Molecular Formula	C59H75N18O14
Molecular Weight	1259.4 g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, dilute acetic acid, DMSO
Endotoxin	< 1.0 EU/mg
Biological Activity	Lamprey gonadotropin-releasing hormone III; involved in regulating reproductive axis function, and can be used in comparative endocrinology, reproductive physiology, and evolutionary research.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

LHRH-Ⅲ, lamprey functions as a neuroendocrine peptide that binds to specific G-protein coupled gonadotropin-releasing hormone receptors in the lamprey pituitary. This binding activates phospholipase C-mediated signaling pathways, leading to increased intracellular calcium levels and protein kinase C activation. The downstream effects stimulate the synthesis and release of gonadotropins, which regulate gonadal development, steroidogenesis, and reproductive behaviors. The peptide exhibits distinct receptor-binding properties compared to mammalian GnRH isoforms, providing insights into the evolutionary adaptation of neuroendocrine systems. Its structural features, including conserved N-terminal pyroglutamate and C-terminal amidation, contribute to receptor recognition and metabolic stability in aquatic environments.

2.PRODUCT INDICATIONS

Comparative Endocrinology: Study of GnRH system evolution across vertebrate lineages

Reproductive Biology: Investigation of lamprey reproductive physiology and spawning regulation

Evolutionary Neuroscience: Research on neuropeptide system conservation and diversification

Neuroendocrine Research: Analysis of hypothalamic-pituitary-gonadal axis regulation in basal vertebrates

Conservation Physiology: Assessment of environmental impacts on lamprey reproduction

Peptide Evolution: Structural and functional studies of GnRH family diversification

3.CLINICAL EFFICACY OF PRODUCT

High Purity: ≥95% by RP-HPLC with mass spectrometry confirmation of lamprey-specific sequence

Species Authenticity: Verified amino acid sequence corresponding to native lamprey LHRH-Ⅲ

Biological Activity: Validated in receptor binding assays and physiological studies

Research Reproducibility: Consistent performance in comparative and functional assays

Quality Documentation: Certificate of Analysis provided with purity, mass spec, and analytical data

Technical Support: Access to application guidance for evolutionary and comparative research

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

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