β-Lipotropin (61-64)

<p>β-Lipotropin (61-64) is a high-purity synthetic tetrapeptide corresponding to the 61-64 amino acid fragment of human β-lipotropin, with the sequence Tyr-Gly-Gly-Phe (YGGF). This peptide represents the core sequence of methionine-enkephalin, an endogenous opioid peptide that plays a crucial role in pain modulation, stress response, and neuroendocrine regulation. Manufactured under stringent quality controls with H…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	β-Lipotropin (61-64)
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C22H26N4O6
Molecular Weight	442.48g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, dilute acetic acid, DMSO
Endotoxin	< 1.0 EU/mg
Biological Activity	The short C-terminal fragment of β-Lipotropin corresponds to the sequence of methionine-enkephalin (YGGF), exhibiting opioid-like activity. It can bind to opioid receptors and participate in pain modulation.
Storage Conditions	Store at -20°C or below, protected from light and moisture. After reconstitution, aliquot and store at -20°C.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

β-Lipotropin (61-64) functions as an endogenous opioid peptide that binds to and activates μ-opioid and δ-opioid receptors in the central and peripheral nervous systems. Upon receptor binding, it triggers G-protein coupled signaling pathways, leading to inhibition of adenylate cyclase activity, reduction of intracellular cAMP levels, and modulation of ion channel activity (particularly potassium channel activation and calcium channel inhibition). These molecular events result in decreased neurotransmitter release, hyperpolarization of neurons, and inhibition of pain signal transmission. The peptide's Tyr-Gly-Gly-Phe sequence constitutes the conserved opioid motif essential for receptor recognition and activation. Its short length allows for precise investigation of structure-activity relationships and receptor binding domains without interference from larger peptide regions.

2.PRODUCT INDICATIONS

Opioid Receptor Research: Investigation of μ and δ opioid receptor binding, activation, and signaling

Pain Modulation Studies: Analysis of analgesic mechanisms and endogenous pain control systems

Structure-Activity Relationship: Study of opioid peptide-receptor interactions and pharmacophore mapping

Neuropharmacology: Research on opioid system function in neurological and psychiatric disorders

Drug Discovery: Screening for opioid receptor agonists, antagonists, and modulators

Comparative Pharmacology: Study of opioid peptide conservation across species

3.CLINICAL EFFICACY OF PRODUCT

Biological Activity: Validated in opioid receptor binding assays and functional studies

Sequence Authenticity: Verified Tyr-Gly-Gly-Phe sequence corresponding to β-lipotropin 61-64

Research Reproducibility: Consistent performance in receptor binding, signaling, and functional assays

Low Endotoxin:<1.0 eu="">

Technical Support: Access to application guidance for opioid receptor and neuropeptide research

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.