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Chemicals
Mastoparan X CAS NO.72093-22-2
<p>Mastoparan X (CAS NO. 72093-22-2) is a synthetic, 14-amino acid amphipathic peptide toxin, originally derived from wasp venom. Known for its potent membrane-active and cell-penetrating properties, it is a high-purity research-grade reagent widely used as a direct G-protein activator and a model for studying membrane interactions and signal transduction pathways.</p>
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Mastoparan X |
| CAS NO. | 72093-22-2 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C73H126N20O15S |
| Molecular Weight | 1556.01g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, 0.1 M acetic acid, or DMSO at a concentration ≥ 1 mg/mL. |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Potent activator of G-proteins; induces histamine release from mast cells; exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria. |
| Storage Conditions | Store long-term at -20°C to -80°C; avoid repeated freeze-thaw cycles. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Mastoparan X functions primarily by directly binding to and activating heterotrimeric G-proteins (Gα subunits, particularly Gi/o), bypassing traditional receptor activation. It inserts into phospholipid membranes, forming pores or destabilizing bilayer integrity, which facilitates its cell-penetrating ability and leads to downstream effects such as phospholipase activation, calcium mobilization, and histamine release from mast cells.
2.PRODUCT INDICATIONS
This peptide is indicated for research applications in cell biology, pharmacology, and biochemistry. It is used as a tool compound for: studying G-protein coupled receptor (GPCR)-independent G-protein signaling, investigating mast cell degranulation, exploring mechanisms of antimicrobial and anticancer peptides, and as a model for membrane pore formation and peptide-lipid interactions.
3.CLINICAL EFFICACY OF PRODUCT
As a research tool, Mastoparan X itself is not used for direct clinical application. However, its profound biological activities make it a valuable prototype in preclinical studies. Research utilizing Mastoparan X has contributed significantly to the understanding of G-protein signaling, membrane permeabilization mechanisms, and the design of novel antimicrobial or cell-penetrating peptides with potential therapeutic applications.
4.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
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Global Technology Co., Ltd.
