Mas8

<p>Mas8 Peptide (CAS 2044915-80-2) is a research-grade, selective agonist for the MRGPRX8 receptor, with a molecular formula of C₁₁₁H₁₅₉N₂₉O₂₈S and a molecular weight of 2456.70 g/mol. Manufactured to ≥98% purity via RP-HPLC, this lyophilized peptide is a critical tool for studying peripheral pain signaling, anti-inflammatory pathways, and sensory neuron function, offering consistent batch-to-batch performance for p…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Mas8
CAS NO.	\
Appearance	White to off-white lyophilized powder
Molecular Formula	C70H131N21O15
Molecular Weight	1506.96g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water (≥10 mg/mL), dilute acetic acid, or 0.01M PBS
Endotoxin
Biological Activity	Potent and selective agonist for the MRGPRX8 receptor, mediating analgesic and anti-inflammatory effects by modulating peripheral sensory neuron signaling. Validated for pain research and inflammation pathway studies.
Storage Conditions	20°C to -80°C in a desiccated environment, avoiding repeated freeze-thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Mas8 Peptide acts as a potent, selective agonist for the MRGPRX8 receptor, which is primarily expressed on peripheral sensory neurons. Upon binding, it triggers intracellular signaling cascades that modulate neuron excitability, leading to reduced pain perception and suppression of pro-inflammatory cytokine release. This mechanism enables targeted investigation of pain pathways without central nervous system side effects, making it valuable for analgesic drug development.

2.PRODUCT INDICATIONS

Peripheral pain signaling and nociceptor activation

Anti-inflammatory pathway modulation

MRGPRX8 receptor pharmacology

Preclinical development of novel analgesics

Sensory neuron function and neuroinflammation

3.CLINICAL EFFICACY OF PRODUCT

Potent analgesic effects in animal models of inflammatory and neuropathic pain

Significant reduction in pro-inflammatory markers (e.g., TNF-α, IL-6) in peripheral tissues

High selectivity for MRGPRX8, minimizing off-target effects

Potential as a lead compound for next-generation pain therapies with reduced CNS-related side effects

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.