Atrial Natriuretic Peptide Substrate, [pS6] ANF 1-28

<p><strong>Atrial Natriuretic Peptide Substrate, [pS6] ANF 1-28</strong> is a specialized phosphorylated peptide substrate designed for cardiovascular and signal transduction research. It serves as a critical tool for studying natriuretic peptide pathways, kinase/phosphatase activity, and related biological mechanisms.</p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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Peptides

About this product

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Atrial Natriuretic Peptide Substrate, [pS6] ANF 1‑28
CAS NO.
Appearance	White to off-white lyophilized powder
Molecular Formula	C128H206N45PO42S2
Amino Acid Sequence	H‑Ser‑Leu‑Arg‑Arg‑Ser‑Ser‑Cys‑Phe‑Gly‑Gly‑Arg‑Ile‑Asp‑Arg‑Ile‑Gly‑Ala‑Gln‑Ser‑Gly‑Leu‑Gly‑Cys‑Asn‑Ser‑Phe‑Arg‑Tyr‑OH (human ANF 1‑28 with phosphorylated Ser at position 6)
Molecular Weight	3143.5g/mol
Purity (RP-HPLC)	≥95.0% (customizable to ≥98.0%)
Solubility	Soluble in water, dilute acetic acid, or phosphate‑buffered saline (PBS)
Endotoxin	< 1.0 EU/mg
Biological Activity	Phosphorylated ANF derivative; used as a substrate for kinases (e.g., PKG, PKA) or phosphatase studies, and in cardiovascular signal‑transduction research.
Storage Conditions	Store at –20 °C, protected from light and moisture. For long‑term storage, recommend –80 °C.
Stock Location	Stock in USA
MOQ	1mg

1.MECHANISM OF ACTION

This peptide functions as a phosphorylated substrate that binds to natriuretic peptide receptors (e.g., NPR-A/NPR-B) and interacts with key kinases (such as PKG and PKA) or phosphatases. It enables researchers to investigate phosphorylation-dependent signaling events involved in fluid balance, blood pressure regulation, and cardiovascular function.

2.PRODUCT INDICATIONS

Atrial Natriuretic Peptide Substrate, [pS6] ANF 1-28 is widely used in cardiovascular research, kinase/phosphatase activity assays, and studies of natriuretic peptide system dynamics. It is also employed in drug discovery and preclinical investigations targeting heart failure, hypertension, and renal disorders.

3.CLINICAL EFFICACY OF PRODUCT

While this product is intended for research use only, it provides valuable insights into disease mechanisms and helps identify potential therapeutic targets in cardiovascular and renal pathologies. Its application in preclinical models contributes to the development of novel treatments for conditions related to natriuretic peptide dysfunction.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.