[β-Ala8]-Neurokinin A (4-10)

<p>[β-Ala8]-Neurokinin A (4-10) is a synthetic, modified tachykinin peptide fragment and a stabilized analog of Neurokinin A (NKA). This research-grade compound features a β-alanine substitution at position 8, which enhances its metabolic stability against enzymatic degradation. It is a selective and potent agonist for the Neurokinin 2 (NK2) receptor, making it a valuable tool for studying tachykinin signaling, smoo…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	[β-Ala⁸]-Neurokinin A (4-10)
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C35H56N8O10S
Molecular Weight	781 /mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in water (≥1 mg/mL), 0.1% TFA in aqueous solution, dilute acetic acid and DMSO
Endotoxin	≤1.0 EU/mg
Biological Activity	Potent and selective agonist for neurokinin-2 (NK2) receptors
Storage Conditions	Store at ≤ -20°C in a dry, dark, sealed container.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

This analog acts as a potent and selective agonist for the Neurokinin 2 (NK2) receptor. The incorporation of β-alanine at position 8 increases resistance to peptidase cleavage, prolonging its biological activity. Upon binding to the NK2 receptor, it activates the associated Gq protein, triggering the phospholipase C (PLC) pathway.

2.PRODUCT INDICATIONS

This product is indicated for in vitro and in vivo research in pharmacology, smooth muscle physiology, and neurobiology. Key applications include: investigating the role of NK2 receptors in bronchoconstriction, gastrointestinal motility, and bladder function; serving as a stable reference agonist in functional assays using isolated tissue preparations.

3.CLINICAL EFFICACY OF PRODUCT

[β-Ala8]-Neurokinin A (4-10) is a research tool, not a clinical therapeutic. Its efficacy is defined by its utility as a robust and stable pharmacological probe. Research utilizing this analog has been instrumental in delineating the specific physiological roles of NK2 receptor signaling.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

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