Chemicals

Neurokinin B CAS NO.86933-75-7

<p>Neurokinin B (CAS NO. 86933-75-7) is a high‑purity synthetic tachykinin neuropeptide.It is widely used in neuroendocrine, reproductive, and physiological research.<br/></p>

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Neurokinin B
CAS NO.
86933-75-7
Appearance
White to off-white lyophilized powder
Molecular Formula
C55H79N13O14S2
Amino Acid Sequence
H‑Asp‑Met‑His‑Asp‑Phe‑Phe‑Val‑Gly‑Leu‑Met‑NH₂
Molecular Weight
1210.45g/mol 
Purity (RP-HPLC)
≥97.0% (typical commercial grade)
Solubility

Soluble in water, 0.1 M acetic acid, or PBS (pH 7.0‑7.4)

Endotoxin< 1.0 EU/mg
Biological Activity
Tachykinin neuropeptide; binds preferentially to the NK₃ receptor, involved in the regulation of gonadotropin release, pain transmission, and smooth muscle contraction.
Storage Conditions
Store at –20 °C, protected from light and moisture. For long‑term storage, recommend –80 °C.
Stock Location
Stock in USA
MOQ
1mg


1.MECHANISM OF ACTION

Neurokinin B functions primarily by binding to and activating the neurokinin‑3 (NK₃) receptor. This receptor interaction triggers intracellular signaling cascades, influencing the release of gonadotropin‑releasing hormone (GnRH) and other neuroendocrine modulators, thereby playing a key role in the regulation of reproductive and hormonal pathways.


2.PRODUCT INDICATIONS

This peptide is employed in research on reproductive disorders, neuroendocrine regulation, and hormonal feedback mechanisms. It is also applied in studies investigating conditions such as polycystic ovary syndrome (PCOS), hypothalamic amenorrhea, and other disorders linked to GnRH and gonadotropin secretion.


3.CLINICAL EFFICACY OF PRODUCT

Preclinical and clinical data indicate that Neurokinin B modulates GnRH pulse generation and gonadotropin release, supporting its potential as a therapeutic target in reproductive endocrinology. Its role in regulating the hypothalamic‑pituitary‑gonadal axis highlights its relevance for developing treatments for fertility and hormone‑related conditions.


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.