Chemicals

Acetyl Hexapeptide-38 CAS NO.1400634-44-7

<p>Acetyl Hexapeptide-38 is a synthetic peptide cosmetic ingredient designed for topical skin care formulations, featuring an acetylated hexapeptide structure that enhances stability and skin penetration. It is supplied as a high-purity lyophilized powder for incorporation into anti-aging and moisturizing products, targeting improvements in skin hydration, barrier function, and the appearance of fine lines and wrink…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Acetyl Hexapeptide-38
CAS NO.
1400634-44-7
Appearance
White to off-white lyophilized powder
Molecular Formula
C33H50N9O10
Molecular Weight
701.82g/mol 
Purity (RP-HPLC)
≥ 95.0%
Solubility

Soluble in water, phosphate‑buffered saline (PBS), or dilute aqueous solutions. It is recommended to first dissolve in a small volume of sterile water to prepare a 0.1–1.0 mg/mL stock solution.

Endotoxin< 1.0 EU/mg
Biological Activity
Acetyl Hexapeptide‑38 is a synthetic peptide designed for cosmetic applications, reported to support skin barrier function, improve hydration, and enhance skin elasticity. Its bioactivity is often evaluated in cell‑based assays related to collagen production or moisturization.
Storage Conditions
Lyophilized powder: Store desiccated at –20 °C or below, protected from light, for long‑term stability.
Reconstituted solution: Aliquot and store at ≤ –20 °C; avoid repeated freeze‑thaw cycles.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Acetyl Hexapeptide-38 penetrates the stratum corneum and acts on dermal fibroblasts to stimulate the synthesis of collagen and elastin, while promoting the production of hyaluronic acid and other glycosaminoglycans to enhance dermal hydration and skin plumpness. It also modulates signaling pathways involved in extracellular matrix remodeling and supports the expression of proteins that strengthen the dermal-epidermal junction, thereby improving skin barrier integrity and reducing transepidermal water loss for firmer, more resilient skin.

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2.PRODUCT INDICATIONS

This ingredient is indicated for research and development of topical cosmetic formulations aimed at anti-aging, skin hydration, and barrier restoration, including facial serums, creams, and eye contour products. It is used in in vitro and ex vivo models to evaluate collagen synthesis, hyaluronic acid production, and skin barrier function, with applications in products addressing fine lines, wrinkles, dryness, and loss of elasticity associated with aging and environmental stress.

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3.CLINICAL EFFICACY OF PRODUCT

Clinical studies on formulations containing Acetyl Hexapeptide-38, often in combination with other peptides and moisturizing agents, report improvements in skin hydration, elasticity, and reduction in the appearance of fine lines after 4 to 12 weeks of topical application. However, data are primarily from manufacturer-sponsored trials and small-scale studies; robust, independent clinical evidence for its standalone efficacy is limited, and it remains a cosmetic ingredient with supportive but preliminary validation for aesthetic benefits.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.


5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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