Acetyl Pentapeptide-1 CAS NO.823202-99-9

<p>Acetyl Pentapeptide-1 (CAS NO. 823202-99-9) is a synthetic, acetylated pentapeptide engineered for advanced cosmetic applications, primarily to reduce the appearance of expression lines and wrinkles. It is often referred to by the trade name <strong>Argireline®</strong>. This peptide functions as a topical neuromodulator, specifically targeting and reducing muscle contractions that lead to dynamic wrinkles, offer…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	Acetyl Pentapeptide-1
CAS NO.	823202-99-9
Appearance	White to off-white lyophilized powder
Molecular Formula	C23H51N9O10
Molecular Weight	805.94 g/mol
Purity (RP-HPLC)	≥98%
Solubility	Soluble in water (≥25 mg/mL), easily soluble in DMSO or dilute acetic acid
Endotoxin	< 1.0 EU/mg
Biological Activity	Promotes collagen synthesis, inhibits matrix metalloproteinase (MMP) activity; demonstrated anti-wrinkle efficacy in in vitro and in vivo studies
Storage Conditions	Store at -20°C to -80°C in a dry, dark environment; avoid repeated freeze-thaw cycles
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

Acetyl Pentapeptide-1 acts as a competitive inhibitor of the SNARE complex, a crucial protein assembly required for the release of neurotransmitters like acetylcholine at the neuromuscular junction. Its amino acid sequence mimics a portion of the SNAP-25 protein, one of the core components of the SNARE complex. By binding to the complex, it interferes with the proper docking and fusion of synaptic vesicles, effectively reducing the release of acetylcholine.

2.PRODUCT INDICATIONS

This product is indicated for cosmetic science and the formulation of premium anti-aging skincare products. Key applications include: as a primary active in anti-wrinkle serums, creams, and eye treatments designed to reduce expression lines; in formulations marketed for "botox-like" or muscle-relaxing effects via topical application; for targeting crow's feet, forehead lines, and frown lines; and as part of professional skincare regimens aimed at preventing and minimizing the depth of dynamic wrinkles.

3.CLINICAL EFFICACY OF PRODUCT

Acetyl Pentapeptide-1 (Argireline®) is a clinically validated cosmetic bioactive. Multiple in vitro and clinical studies on formulations containing this peptide have demonstrated its efficacy. Results typically show a significant reduction in the depth and severity of expression lines (up to 30% improvement in wrinkle depth in some studies), a visible smoothing of the skin's surface, and an overall more relaxed and youthful appearance. It is recognized as a safe and effective topical ingredient for reducing the signs of aging caused by repetitive facial muscle movements.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.