Chemicals

Acetyl Tetrapeptide-40 CAS NO.1472633-28-5

<p><strong>Acetyl Tetrapeptide-40</strong> is a synthetic, acetylated peptide engineered for advanced cosmetic applications, specifically designed to <strong>promote skin firmness and elasticity by stimulating the production of key extracellular matrix (ECM) components</strong>. This biomimetic peptide targets the dermal-epidermal junction (DEJ) and the dermal layer, helping to combat signs of sagging and loss of sk…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
 Copper tripeptide-3  (Synonyms: AHK-Cu)
CAS NO.
1472633-28-5
Appearance
White to off-white lyophilized powder
Molecular Formula
 C₁₇H₂₉N₅O₉
Molecular Weight
 447.44 g/mol
Purity (RP-HPLC)
≥ 95.0%
Solubility

Soluble in water (NLT 5 mg/ml), methanol, and DMSO

Endotoxin< 1.0 EU/mg
Biological Activity
Anti-inflammatory; inhibits IL-6/IL-8 release, reduces skin redness, erythema, telangiectasia; photoprotective (UV-induced inflammation modulation); prevents MMP activation to preserve collagen
Storage Conditions
Store at 2-8°C in a dry, dark environment; avoid repeated freeze-thaw cycles.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Acetyl Tetrapeptide-40 acts as a signaling peptide that stimulates dermal fibroblasts, the cells responsible for producing skin's structural proteins. Its specific mechanism includes:
  1. Stimulation of Fibroblast Activity: The peptide is recognized by specific receptors on the surface of fibroblasts, triggering intracellular signaling cascades.

  2. Enhanced Synthesis of ECM Components: This signaling leads to the upregulated production of collagen types I, III, and IV, elastin, and fibronectin. These proteins are fundamental for skin strength, elasticity, and resilience.

  3. Reinforcement of the Dermal-Epidermal Junction (DEJ): By promoting the synthesis of collagen IV (a primary component of the DEJ) and other anchoring proteins, it helps strengthen the critical connection between the dermis and epidermis. This can improve skin firmness and counteract sagging.

  4. Improvement of Skin Micro-architecture: The overall increase in dermal matrix density contributes to thicker, more toned-looking skin.


2.PRODUCT INDICATIONS

This product is indicated for cosmetic science and the formulation of high-performance firming and anti-aging skincare products. Key applications include:
  • As a primary active in firming serums, lifting creams, and neck treatments targeting loss of skin elasticity and sagging.

  • In products designed to improve skin density, tonicity, and overall facial contour.

  • For formulations aimed at strengthening the dermal-epidermal junction and improving skin's structural integrity.

  • As a key component in comprehensive anti-aging regimens that address both wrinkles and loss of firmness.

  • In products for preventative aging care to help maintain skin's youthful support structure.


3.CLINICAL EFFICACY OF PRODUCT

Acetyl Tetrapeptide-40 is supported by in vitro data demonstrating its stimulatory effect on fibroblast collagen production. Clinical studies on cosmetic formulations containing this peptide show measurable efficacy:
  • Significant Improvement in Skin Firmness and Elasticity: Objective measurements (e.g., cutometry) show enhanced skin viscoelastic properties.

  • Visible Reduction in Signs of Sagging: Subjective assessments and photographic analysis indicate a more lifted and toned appearance, particularly in areas like the jawline and cheeks.

  • Improved Skin Density and Smoothness: The skin appears plumper and more refined due to the enhanced dermal matrix.

  • Results that Contribute to a More Youthful Facial Contour: Regular use helps counteract the effects of gravity and volume loss associated with aging.

Its efficacy validates its role as a targeted ingredient for skin firming and lifting.


    4.Certificate

    • GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

    Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


    We prioritize:

    1.A rigorous quality management system

    2.Batch traceability and stability data

    3.Professional laboratory testing and validation

    4.Compliance with international trade standards


    Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

    5.DELIVERY & SHIPPING

    We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

    Professional and Secure Packaging

    Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

    We can also customize packaging according to customer needs.

    Shipping Methods 

    Main Method: International Air Freight

    We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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    Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

    We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


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    If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510