C. difficile Toxin B (529 - 536)

<p>C. difficile Toxin B (529-536) is a synthetic linear octapeptide fragment derived from residues 529 to 536 of Clostridium difficile toxin B, provided as a high-purity lyophilized powder for immunological research. This peptide serves as a defined antigenic epitope for antibody generation, epitope mapping, and T-cell stimulation studies, enabling precise investigation of host immune responses to C. difficile infec…

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TECHNICAL SPECIFICATIONS

Item	Specification
Product Name	C. difficile Toxin B (529 - 536)
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C48H71N13O15
Molecular Weight	1070.18g/mol
Purity (RP-HPLC)	≥ 95.0%
Solubility	Soluble in water, phosphate‑buffered saline (PBS), or dilute aqueous solutions. It is recommended to first dissolve in a small volume of sterile water to prepare a 0.1–1.0 mg/mL stock solution.
Endotoxin	< 1.0 EU/mg
Biological Activity	This peptide corresponds to a linear fragment (residues 529‑536) of C. difficile toxin B. It may be used as an antigen for antibody production, epitope mapping, or T‑cell stimulation studies related to C. difficile infection and vaccine research. Bioactivity should be validated in relevant immunological assays.
Storage Conditions	Lyophilized powder: Store desiccated at –20 °C or below, protected from light, for long‑term stability. Reconstituted solution: Aliquot and store at ≤ –20 °C; avoid repeated freeze‑thaw cycles.
Stock Location	Stock in USA
MOQ	1g

1.MECHANISM OF ACTION

As a linear peptide epitope, this fragment does not exhibit the enzymatic or cytotoxic activity of full-length toxin B. Its mechanism is immunological: when presented by antigen-presenting cells via MHC molecules, it engages T-cell receptors to stimulate specific T-cell responses. Alternatively, it binds to B-cell receptors or pre-existing antibodies, eliciting or detecting humoral immune responses directed against this specific region of toxin B, facilitating the study of antigen-antibody interactions and immune recognition.

2.PRODUCT INDICATIONS

This peptide is indicated for research applications in C. difficile immunology and vaccine development, including epitope mapping of monoclonal and polyclonal antibodies, generation of toxin-specific antibodies, T-cell proliferation and cytokine assays, and validation of diagnostic immunoassays targeting toxin B. It is suitable for academic, pharmaceutical, and diagnostic research focused on understanding host immunity to C. difficile, developing serological tests, and supporting vaccine candidate evaluation.

3.CLINICAL EFFICACY OF PRODUCT

C. difficile Toxin B (529-536) is a research-grade peptide antigen and has no established clinical efficacy or therapeutic use in humans. Its utility lies in preclinical studies where it enables the characterization of immune responses, validation of diagnostic reagents, and support for vaccine development programs, without direct patient application or regulatory approval for clinical intervention.

4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.