Chemicals

MCH-Gene-Overprinted-Polypeptide-14 (rat) CAS NO.182917-44-8

<p>MCH-Gene-Overprinted-Polypeptide-14 (rat) is a synthetic 14-residue peptide (MGOP-14) derived from the rat melanin-concentrating hormone (MCH) gene locus. This peptide is utilized as a research reagent for investigating neuropeptide functions and receptor interactions, particularly in studies related to energy homeostasis and appetite regulation. Its availability supports biochemical assays and in vivo research e…

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TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
MCH-Gene-Overprinted-Polypeptide-14 (rat)
CAS NO.
182917-44-8
Appearance
White to off-white lyophilized powder
Molecular Formula
C80H131N22O18S3
Molecular Weight
1785.26g/mol 
Purity (RP-HPLC)
≥ 95.0%
Solubility

Soluble in water, PBS, or dilute acetic acid. It is recommended to dissolve in sterile water or buffer to prepare stock solutions for biological assays.

Endotoxin< 1.0 EU/mg (Typical for research-grade peptides)
Biological Activity
This peptide is a synthetic analog of the rat MCH-gene-overprinted polypeptide. It is used in research to study the biological functions of the MCH gene locus, including potential roles in cellular uptake, protein transduction, or as a control peptide in studies related to melanin-concentrating hormone pathways.
Storage Conditions
Store at -20°C or lower. For long-term storage, keep desiccated at -20°C. Upon reconstitution, aliquot and store at -20°C to avoid repeated freeze-thaw cycles.
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

The peptide is characterized by its specific amino acid sequence (H-Thr-Ile-His-Cys-Lys-Trp-Arg-Glu-Lys-Pro-Leu-Met-Leu-Met-OH) and is primarily employed as an analytical standard or immunogen in neurobiological research. It aids in the characterization of MGOP-immunoreactive material and is instrumental in studying the colocalization and functional interplay between MCH and somatostatin systems in the hypothalamus.


2.PRODUCT INDICATIONS

This product is indicated for use in research settings focusing on the hypothalamic regulation of feeding behavior and energy balance. It serves as a critical tool for identifying MGOP-like antigens and elucidating the inhibitory roles of pro-somatostatin fragments on neuropeptide secretion, thereby advancing our understanding of neuroendocrine feedback mechanisms.


3.CLINICAL EFFICACY OF PRODUCT

MCH-Gene-Overprinted-Polypeptide-14 (rat) is intended for research purposes only and is not approved for diagnostic or therapeutic use in humans. Its clinical relevance is confined to its utility as a biochemical reagent in preclinical studies investigating neuropeptide pathways and their potential implications in metabolic disorders.


4.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods 
Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.