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Chemicals
Omiganan pentahydrochloride CAS NO.269062-93-3
<p>Omiganan pentahydrochloride is a synthetic cationic antimicrobial peptide (AMP) analog of indolicidin, developed as a broad-spectrum topical agent targeting multidrug-resistant pathogens. It exhibits rapid bactericidal and fungicidal activity against a wide range of Gram-positive and Gram-negative bacteria, including MRSA and Candidaspecies, with a low propensity for inducing resistance, making it a promising can…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Omiganan Pentahydrochloride |
| CAS NO. | 269062-93-3 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C90H127N27O12 |
| Molecular Weight | 779.14g/mol |
| Amino Acid Sequence | ILRWPWWPWRRK-NH₂ (Cationic antimicrobial peptide derivative) |
| Purity (RP-HPLC) | ≥95.0% |
| Solubility | Soluble in water and aqueous buffers (e.g., PBS); slightly soluble in DMSO |
| Endotoxin | < 1.0 EU/mg |
| Biological Activity | Broad-spectrum antimicrobial peptide with activity against bacteria, fungi, and biofilms; studied for topical antisepsis and infection prevention. |
| Storage Conditions | Store at –20°C, protected from light and moisture. |
| Stock Location | Stock in USA |
| MOQ | 10mg |
1.MECHANISM OF ACTION
Omiganan primarily acts by disrupting microbial cell membranes through electrostatic interactions; its cationic structure binds to negatively charged phospholipids, causing rapid membrane depolarization and permeability, leading to cell lysis and death. Unlike traditional antibiotics, this non-receptor-mediated physical mechanism avoids common resistance pathways and is effective against biofilms, providing a robust first-line defense against persistent infections.
2.PRODUCT INDICATIONS
This peptide is indicated for research and development in topical dermatological formulations for inflammatory skin conditions such as acne vulgaris, rosacea, and atopic dermatitis, as well as for antimicrobial coatings on medical devices like central venous catheters to prevent biofilm formation and bloodstream infections in clinical settings.
3.CLINICAL EFFICACY OF PRODUCT
Clinical trials have demonstrated that topical Omiganan significantly reduces bacterial load and improves dysbiosis in atopic dermatitis patients, with phase II studies showing efficacy in reducing inflammatory lesions in acne and rosacea. In catheter-associated infection models, it has shown potent inhibition of fungal and bacterial colonization, underscoring its potential as a preventive antimicrobial agent in high-risk medical environments.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Omiganan #OmigananPentahydrochloride #AntimicrobialPeptide #AMPs #CatheterCoating #MRSA #AntiBiofilm #TopicalAntimicrobial
If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85296236544
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Global Technology Co., Ltd.
