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Chemicals
Aloperine CAS NO.56293-29-9
<p><h3></h3></p><div class="ybc-p">Aloperine is a natural quinolizidine alkaloid extracted from <em>Sophora alopecuroides L.</em>, known for its potent anti-inflammatory, antiviral, and antitumor properties. This versatile compound demonstrates significant efficacy in modulating immune responses and inhibiting viral replication, making it a valuable candidate for research in inflammatory diseases, viral infections, …
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Aloperine |
| CAS NO. | 56293-29-9 |
| Appearance | White to off-white crystalline powder or solid |
| Molecular Formula | C₁₅H₂₄N₂ |
| Molecular Weight | 232.36 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in organic solvents such as DMSO, methanol, ethanol, and chloroform; sparingly soluble in water |
| Endotoxin | Not applicable (Non-endotoxin compound) |
| Biological Activity | Bioactive alkaloid with diverse pharmacological activities, including anti-inflammatory, anti-allergic, anti-arrhythmic, anti-hypertensive, and potential anti-cancer and anti-fibrotic effects. |
| Storage Conditions | Store at 2–8°C, protected from light and moisture. Stable for 12 months when stored properly. |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
Aloperine exerts its effects by modulating multiple signaling pathways, including the PI3K/Akt, NF-κB, and NLRP3 inflammasome pathways. It inhibits the release of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6, thereby reducing inflammation and oxidative stress. Additionally, Aloperine interferes with viral entry and replication by disrupting endocytosis and membrane fusion processes, and it induces apoptosis and cell cycle arrest in cancer cells through mitochondrial and caspase-dependent mechanisms.
2.PRODUCT INDICATIONS
This product is primarily indicated for research in inflammatory and autoimmune conditions, such as allergic contact dermatitis and rheumatoid arthritis, due to its immunomodulatory effects. It is also suitable for studies on viral infections, including HCV and SARS-CoV-2, as well as various cancers, leveraging its ability to inhibit proliferation and induce apoptosis in malignant cells. Researchers focusing on cardiovascular protection and ischemia-reperfusion injury will find its antioxidant and anti-apoptotic properties particularly relevant.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies have demonstrated that Aloperine significantly alleviates symptoms in models of allergic dermatitis by reducing ear swelling and cytokine levels. In cancer research, it inhibits tumor growth and metastasis in lung, colon, and liver cancer models. Furthermore, it shows protective effects against cardiac and pulmonary ischemia-reperfusion injury by mitigating oxidative stress and ferroptosis, highlighting its potential for therapeutic development across multiple disease areas.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Aloperine #NaturalAlkaloid #AntiInflammatory #Antiviral #Anticancer #Immunomodulator #SophoraAlopecuroides #ResearchChemical #PharmaceuticalIntermediate #DrugDiscovery
If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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Global Technology Co., Ltd.
