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Chemicals
Vitamin K2(35) CAS NO.18749-18-3
<p>Vitamin K2(35), chemically known as Menaquinone-4 (MK-4) with CAS number 18749-18-3, is a crucial, fat-soluble form of Vitamin K2. It features a side chain with 4 isoprenoid units. Unlike MK-7, which is primarily produced by bacteria, MK-4 can be synthesized in animals and humans from Vitamin K1. It plays a vital role in calcium metabolism, directing calcium to bones and teeth while inhibiting its deposition in s…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Vitamin K2(35) |
| CAS NO. | 18749-18-3 |
| Appearance | Yellow to orange crystalline powder |
| Molecular Formula | C₃₀H₃₉N₅O₉ |
| Molecular Weight | 648.99 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in ethanol, methanol, acetone, dichloromethane, fats and oils; practically insoluble in water |
| Endotoxin | <0.1 EU/mg |
| Storage Conditions | Store at 2–8°C, sealed, dry, protected from light and oxygen |
| Stock Location | Stock in USA |
| MOQ | 10g |
1.MECHANISM OF ACTION
- Menaquinone-4 (MK-4) functions primarily as a cofactor for the enzyme gamma-glutamyl carboxylase, which activates Vitamin K-dependent proteins (VKDPs). This carboxylation process is essential for the biological activity of key proteins such as osteocalcin (involved in bone mineralization) and Matrix Gla Protein (MGP, a potent inhibitor of vascular calcification). By activating osteocalcin, MK-4 promotes the binding of calcium to the bone matrix. By activating MGP, it prevents calcium deposition in arteries and other soft tissues, supporting cardiovascular health. It also has roles in cell growth regulation and apoptosis.
2.PRODUCT INDICATIONS
This product is intended as a key ingredient for research and development in specific health areas. Primary research and application indications include bone health (for studies on osteoporosis, bone mineral density, and fracture prevention), cardiovascular health (for research on arterial stiffness, vascular calcification, and cardiovascular risk management), dental health (for studying tooth mineralization), and general health (for investigating its role in cellular health, inflammation, and age-related conditions). It is essential for formulating dietary supplements, functional foods, and topical cosmetics.
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
3.CLINICAL EFFICACY OF PRODUCT
Note: Efficacy information is based on scientific research and is not an evaluation of approved drug claims.Clinical and epidemiological studies on Menaquinone-4 (MK-4) demonstrate significant potential. Research indicates that supplemental MK-4 can help reduce bone loss and fracture incidence in postmenopausal women with osteoporosis. It shows promise in slowing the progression of vascular calcification, potentially reducing cardiovascular risk. Studies also suggest benefits for improving insulin sensitivity and supporting dental health. These findings underpin its established use in specific markets (e.g., Japan) and its growing importance in global health product development.
4.Certificate
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:852 7084 6510
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Global Technology Co., Ltd.
