Bz-Val-Gly-Arg-pNA·HCl CAS NO.64815-80-1

TECHNICAL SPECIFICATIONS

1.MECHANISM OF ACTION

The product functions as a selective substrate for serine proteases, particularly those recognizing the Val-Gly-Arg (VGR) sequence. Its mechanism involves the specific hydrolysis of the amide bond between the arginine residue and the p-nitroaniline group by the target enzyme. This cleavage event liberates the yellow-colored p-nitroaniline, which can be quantified spectrophotometrically at 405 nm, providing a direct and linear measure of enzymatic velocity and inhibitor potency.

2.PRODUCT INDICATIONS

This substrate is indicated for the quantitative determination of thrombin and urokinase-type plasminogen activator (uPA) activities in research settings. It is suitable for use in kinetic assays, high-throughput screening of anticoagulant drugs, and quality control testing of therapeutic enzymes. The product is intended for use by biochemists, pharmacologists, and diagnostic kit manufacturers focusing on hemostasis and thrombosis research.

3.CLINICAL EFFICACY OF PRODUCT

While not a therapeutic agent itself, the clinical efficacy of this product lies in its role as a critical reagent in the development and validation of diagnostic assays for coagulation disorders. Its high susceptibility and low Km value ensure sensitive detection of enzyme levels, which is crucial for accurately monitoring patient plasma samples for hypercoagulable states or for assessing the potency of heparin and direct thrombin inhibitors in clinical laboratories.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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