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Chemicals
1,2,3,4,6-O-pentagalloylglucose CAS NO.14937-32-7
<p>1,2,3,4,6-O-Pentagalloylglucose (PGG) is a high-purity natural gallotannin monomer sourced from plants like gallnuts and mango. This potent polyphenol is characterized by its exceptional antioxidant capacity and broad-spectrum bioactivity. It is supplied as a stable, fine white to off-white powder with HPLC purity typically ≥98%, making it an ideal reference standard and active ingredient for research and develop…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | 1,2,3,4,6-O-pentagalloylglucose |
| CAS NO. | 14937-32-7 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C41H32O26 |
| Molecular Weight | 940.68 g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in DMSO, methanol, ethanol; slightly soluble in water |
| Endotoxin | ≤ 0.05 EU/mg |
| Biological Activity | Potent antioxidant, anti-inflammatory, anticancer, antiviral activity |
| Storage Conditions | Store at 2–8°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
PGG exerts its effects through multi-target mechanisms, primarily acting as a powerful free radical scavenger and signaling pathway modulator. It induces apoptosis and autophagy in cancer cells by inhibiting GSK3β/β-catenin and JAK2/STAT3 pathways, while its anti-inflammatory action is mediated through suppression of NF-κB and NLRP3 inflammasome activation. Additionally, it activates the Nrf2/HO-1 pathway for cytoprotection and inhibits viral entry and replication through direct interaction with viral proteins.
2.PRODUCT INDICATIONS
This product is indicated for scientific research in oncology (breast, liver, colorectal cancer), metabolic disorders (diabetes, obesity), and chronic inflammation (arthritis, vascular inflammation). It is also suitable for developing anti-aging skincare products due to its elastin-stabilizing and antioxidant properties, as well as for antiviral formulation research targeting HBV, HIV, and coronaviruses. Primary users include academic researchers, pharmaceutical R&D teams, and nutraceutical developers.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies demonstrate that PGG significantly inhibits tumor growth and metastasis in models of triple-negative breast cancer and hepatocellular carcinoma, showing synergistic effects with conventional chemotherapeutics. In metabolic studies, it improves insulin sensitivity and reduces hyperglycemia in diabetic models. Clinical-relevant efficacy includes cardioprotection against ischemia-reperfusion injury and neuroprotection by inhibiting amyloid-beta aggregation, positioning it as a promising lead compound for drug development.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags:Pentagalloylglucose, PGG, Gallotannin, Antioxidant, Anti-cancer, Anti-inflammatory, Anti-diabetic, Natural polyphenol, Research chemical, Bioactive compound, Drug discovery, Apoptosis inducer, Autophagy inducer, NF-κB inhibitor, Nrf2 activator, Anti-aging, Anti-viral, Metabolic syndrome, Skin care ingredient, Pharmaceutical intermediate, Supplier, Manufacturer, Bulk order, Pharmaceutical.
If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553
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Global Technology Co., Ltd.
