Chemicals

Narirutin CAS NO.108815-81-2

<p>Narirutin is a naturally occurring citrus flavonoid primarily extracted from oranges, grapefruits, and tangerines. As a key bioactive compound in citrus fruits, it is widely utilized in the nutraceutical, pharmaceutical, and cosmetic industries for its potent antioxidant and anti-inflammatory properties. This product is commonly formulated into dietary supplements to support cardiovascular and cognitive health, a…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product

Product information from the supplier.



TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
Narirutin
CAS NO.
108815-81-2
Appearance
White to off-white powder
Molecular Formula
C27H32O14
Molecular Weight
580.53 g/mol
Purity (RP-HPLC)
≥ 98.0%
Solubility
Soluble in DMSO, methanol; slightly soluble in water; insoluble in hexane
Endotoxin< 0.1 EU/mg
Biological Activity
Potent antioxidant, anti-inflammatory, lipid-lowering, and vascular protective effects
Storage Conditions
Store at -20°C, protected from light and moisture
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

Narirutin exerts its biological effects primarily by modulating key cellular signaling pathways and enzyme activities. It functions as a powerful antioxidant by neutralizing free radicals and enhancing endogenous antioxidant defenses like superoxide dismutase (SOD). Its anti-inflammatory action is mediated through the inhibition of NF-κB and MAPK pathways, reducing the production of pro-inflammatory cytokines such as TNF-α and IL-6. Additionally, narirutin demonstrates neuroprotective effects by inhibiting BACE-1 activity (key in amyloid-beta formation) and modulating microglial activation via the JAK2/STAT3 pathway, while its metabolic benefits involve the inhibition of carbohydrate-digesting enzymes and pancreatic lipase.

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2.PRODUCT INDICATIONS

This product is indicated for individuals seeking natural support for metabolic health, including blood glucose and lipid management, as well as those with conditions related to oxidative stress and chronic inflammation, such as cardiovascular concerns or early-stage metabolic syndrome. It is also suitable for adults focusing on cognitive maintenance and neuroprotection, particularly for memory and mood support, and for consumers looking for natural anti-aging and anti-photoaging ingredients in skincare formulations. Additionally, it may benefit individuals with mild hypertension or endothelial dysfunction seeking natural vasodilatory support.

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3.CLINICAL EFFICACY OF PRODUCT

Clinical and preclinical studies have demonstrated that narirutin-rich formulations significantly improve endothelial function and reduce systolic blood pressure in individuals with mild hypertension. Human trials involving flavanone-rich orange juice (a key source of narirutin) have shown acute improvements in cerebral blood flow and cognitive performance, supporting its role in neurohealth. In dermatological applications, clinical studies on green mandarin extract (rich in narirutin) have confirmed significant improvements in skin wrinkle depth, roughness, and collagen density after 12 weeks of use, validating its efficacy as a functional anti-aging ingredient.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


HotTags:Narirutin,  CitrusFlavonoid,  NaturalAntioxidant,  AntiInflammatory,  Neuroprotection,  HealthyAging,  Nutraceuticals,  SkinCareIngredients,  CognitiveHealth,  MetabolicHealth, Supplier, Manufacturer, Bulk order,  Pharmaceutical.


If you have any product requirements, please send an email to:info@huanqiukeji9.com;whatsapp:85246842553