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Chemicals
[Tyr11]-Somatostatin-14 CAS NO.59481-27-5
<p>[Tyr¹¹]-Somatostatin-14 is a high-purity, research-grade peptide analog designed to support advanced studies in endocrine regulation and neurotransmission. Its tyrosine substitution at position 11 enhances experimental utility through increased stability and detectability, making it suitable for binding assays, dose-response curves, and mechanistic investigations in both academic and industrial R&D settings. Rese…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name[Tyr¹¹]-Somatostatin-14 | [Tyr¹¹]-Somatostatin-14 |
| CAS NO. | 59481-27-5 |
| Appearance | White to off-white crystalline powder |
| Molecular Formula | C76H104N18O20S2 |
| Molecular Weight | 1653.91g/mol |
| Purity (RP-HPLC) | ≥ 98.0% |
| Solubility | Soluble in water or acetic acid (1–5 mg/mL); insoluble in organic solvents |
| Endotoxin | ≤ 1.0 EU/mg (Suitable for cell culture and in vitro assays) |
| Biological Activity | Potent inhibitor of growth hormone, insulin, glucagon, gastrin, and secretin release; modulates neuroendocrine signaling |
| Storage Conditions | Lyophilized powder: Store at -20°C, protected from light and moisture (stable 24–36 months). Reconstituted solutions: Store at 2–8°C for up to 2 weeks or -20°C for up to 3 months |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
[Tyr¹¹]-Somatostatin-14 exerts its effects by binding to somatostatinceptors (S reSTR1–SSTR5) expressed on endocrine cells, neurons, and immune cells, triggering intracellular signaling cascades that inhibit adenylate cyclase, reduce cAMP levels, and suppress calcium influx. This leads to the downregulation of hormone secretion — including growth hormone, insulin, glucagon, gastrin, and secretin — while also modulating neurotransmitter release and cellular proliferation. Its Tyr¹¹ modification improves resistance to enzymatic degradation and enhances affinity for certain receptor subtypes, allowing for more precise pharmacological profiling.
2.PRODUCT INDICATIONS
This product is indicated for use in research applications involving neuroendocrine physiology, metabolic disease modeling, oncology (particularly neuroendocrine tumors), and peptide-drug development. It is especially valuable for scientists investigating somatostatin receptor pharmacology, designing radiolabeled analogs for imaging, or evaluating therapeutic agents targeting hormonal imbalances. It is not intended for human or veterinary therapeutic use.
3.CLINICAL EFFICACY OF PRODUCT
While [Tyr¹¹]-Somatostatin-14 is not approved for clinical use, preclinical studies demonstrate its efficacy in inhibiting excessive hormone secretion in experimental models of acromegaly, insulinoma, and gastrinoma. Its ability to suppress pathological signaling pathways makes it a useful surrogate for evaluating next-generation somatostatin analogs or radiopharmaceuticals. In vitro data consistently show dose-dependent inhibition of target hormone release, supporting its role as a benchmark compound in translational research.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: PeptideResearch #SomatostatinAnalog #Neuroendocrinology #HormoneRegulation #LabChemical #ResearchGradePeptide #BiochemicalTool #SSTRReceptor #EndocrineDisorderModel #AcademicResearchSupply
If you have any product requirements, please send an email to:sales@huanqiukeji9.com;whatsapp:85244219157
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Global Technology Co., Ltd.
