Image not available
Chemicals
Lactoferricin B25 CAS NO.146897-68-9
<p>Lactoferricin B25 (Lfcin B25) is a cationic antimicrobial peptide derived from the N-terminal region of bovine lactoferrin. It exhibits broad-spectrum activity against bacteria, fungi, and viruses while also demonstrating immunomodulatory and anticancer properties. This research-grade peptide is characterized by its high selectivity for microbial membranes and its ability to modulate host immune responses, making…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
Source categories
About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Lactoferricin B25 |
| CAS NO. | 146897-68-9 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₄₁H₂₂₄N₄₆O₁₉S₃ |
| Molecular Weight | 3095.7 g/mol |
| Purity (RP-HPLC) | ≥ 95.0% |
| Solubility | Soluble in water, acidic solutions; insoluble or poorly soluble in neutral buffers |
| Endotoxin | < 0.1 EU/mg (by LAL assay) |
| Biological Activity | Antimicrobial, anticancer, and immunomodulatory activities demonstrated in vitro and in vivo studies |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The peptide exerts its effects by binding to G protein-coupled receptors composed of CLR (calcitonin receptor-like receptor) and RAMP2/3 (Receptor Activity-Modifying Proteins), activating adenylate cyclase to increase intracellular cAMP levels. This signaling cascade promotes nitric oxide (NO) release from endothelial cells, leading to vasodilation. Additionally, it inhibits aldosterone secretion and the renin-angiotensin system (RAS), resulting in reduced vascular resistance, increased renal blood flow, and enhanced natriuresis without triggering reflex tachycardia.
2.PRODUCT INDICATIONS
This peptide is indicated for in vitro and in vivo research applications in microbiology, immunology, and oncology. It is used to study antibacterial and antiviral mechanisms, develop antimicrobial coatings, and explore host-directed therapies against multidrug-resistant infections. Researchers in pharmaceutical R&D also utilize it to investigate novel anticancer agents and immunomodulatory compounds.
3.CLINICAL EFFICACY OF PRODUCT
Preclinical studies show that Lactoferricin B25 effectively reduces bacterial loads, including antibiotic-resistant strains, and inhibits biofilm formation. In cancer models, it induces apoptosis in various cell lines and demonstrates synergistic effects with conventional therapies. Its ability to enhance immune clearance while controlling inflammation highlights its potential as a multifunctional therapeutic candidate.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: LactoferricinB #LfcinB #AntimicrobialPeptide #AMPs #ImmunomodulatoryPeptide #Antibacterial #Antifungal #AnticancerPeptide #InnateImmunity #HostDefensePeptide
If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85296236544
More from this supplier
Global Technology Co., Ltd.
