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Chemicals
BNP-32 ,porcine CAS NO.117345-87-6
<p>Porcine BNP-32 (brain natriuretic peptide, 32-amino-acid porcine isoform) is a natriuretic peptide structurally analogous to human BNP-32, serving as a critical research tool for studying cardiac function, heart failure diagnostics, and neurohormonal regulation. It exhibits high selectivity for natriuretic peptide receptors (NPR-A/B), driving cyclic guanosine monophosphate (cGMP)-dependent signaling to modulate f…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | BNP-32 ,porcine |
| CAS NO. | 117345-87-6 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₄₉H₂₅₀N₅₂O₄₄S₃ |
| Molecular Weight | 3495.9g/mol |
| Purity (RP-HPLC) | ≥95% |
| Solubility | Soluble in water, 0.1 M acetic acid, or 10% DMSO solution |
| Endotoxin | <1 EU/mg |
| Biological Activity | Potent natriuretic, vasodilatory, and anti-fibrotic activity via activation of NPR-A receptor, increasing cGMP levels; used for cardiac function research, heart failure diagnostics, and neurohormonal regulation studies |
| Storage Conditions | Store at -20°C, protected from light and moisture; avoid repeated freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
This product is indicated for preclinical research in cardiovascular science, including (1) validating cardiac biomarkers in porcine models of heart failure, hypertension, or myocardial infarction; (2) studying neurohormonal feedback mechanisms in fluid overload and pressure overload conditions; (3) screening therapeutic agents targeting natriuretic peptide pathways; and (4) developing diagnostic assays (e.g., ELISA, immunoassays) for porcine or cross-species BNP detection. It supports applications in basic research, drug discovery, and translational medicine, particularly for teams investigating species-specific cardiac physiology or peptide therapeutics for cardiovascular diseases.
2.PRODUCT INDICATIONS
In preclinical porcine models of heart failure, BNP-32 administration demonstrates dose-dependent reductions in left ventricular end-diastolic pressure, pulmonary capillary wedge pressure, and systemic vascular resistance, alongside improved cardiac output and renal sodium excretion. These effects correlate with reduced myocardial hypertrophy, fibrosis, and inflammation, mirroring human BNP-32’s cardioprotective benefits. While clinical efficacy in humans requires further study, porcine BNP-32’s structural and functional homology to human BNP-32 validates its use as a surrogate for exploring human cardiac pathophysiology and therapeutic responses, providing robust data for translational research and potential peptide-based interventions.
3.CLINICAL EFFICACY OF PRODUCT
Explore Porcine BNP-32 (CAS 117345-87-6) for cutting-edge cardiovascular research—ideal for cardiac biomarker validation, heart failure modeling, and neurohormonal pathway studies. Our high-purity peptide reagent supports preclinical assays, drug screening, and diagnostic assay development with species-specific relevance to porcine (and cross-species) cardiac physiology.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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Global Technology Co., Ltd.
