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Chemicals
Bradykinin Potentiator C CAS NO.30953-20-9
<p>Bradykinin Potentiator C is a synthetic tripeptide (Arg-Pro-Pro) identical to the N-terminal fragment of bradykinin. Historically identified from snake venom, it functions as a pharmacological enhancer of endogenous bradykinin activity rather than a direct receptor agonist. This high-purity peptide is primarily utilized in cardiovascular and inflammation research to amplify the hypotensive and vasodilatory effect…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Bradykinin Potentiator |
| CAS NO. | 30953-20-9 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C51H77N11O13 |
| Molecular Weight | 380.44g/mol |
| Purity (RP-HPLC) | ≥95% |
| Solubility | Soluble in water or 0.1% TFA in water; insoluble in neutral buffer |
| Endotoxin | <1.0 EU/mg (LAL test, typical) |
| Biological Activity | Enhances bradykinin-induced vasodilation and permeability in vitro/in vivo |
| Storage Conditions | Store at -20°C, protected from light and moisture; avoid repeated freeze-thaw |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The peptide potentiates bradykinin's effects primarily by inhibiting angiotensin-converting enzyme (ACE), which normally degrades bradykinin into inactive fragments. By competing for the active site of ACE, it reduces the enzymatic breakdown of endogenous bradykinin, thereby prolonging its half-life and enhancing its availability at B₂ receptors. This indirect mechanism leads to sustained elevation of nitric oxide and prostaglandins, resulting in amplified vasodilation, increased vascular permeability, and prolonged hypotension in experimental models.
2.PRODUCT INDICATIONS
This product is indicated for research applications where amplification of the kinin system is desired, such as in studies of septic shock, hypertension, and inflammatory edema. It is used to investigate the therapeutic potential of kinin potentiation in ischemic conditions, to screen for novel ACE inhibitors, and to model diseases characterized by dysregulated bradykinin metabolism. Researchers in pharmacology and toxicology also utilize it to study venom-derived peptides and their evolutionary adaptations.
3.CLINICAL EFFICACY OF PRODUCT
In preclinical models, Bradykinin Potentiator C significantly enhances the magnitude and duration of bradykinin-induced vasodilation and blood pressure reduction. Studies demonstrate its ability to increase vascular permeability and potentiate pain responses when co-administered with bradykinin. While not used clinically, its efficacy in amplifying kinin effects supports its role as a reference compound for developing drugs that target ACE or seek to modulate bradykinin bioavailability for cardiovascular and inflammatory therapies.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: BradykininPotentiatorC #KininAmplifier #ACEinhibitor #VasoactivePeptide #SnakeVenomPeptide #VasodilationResearch #BradykininResearch #PeptidePotentiator
If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:852944969439
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Global Technology Co., Ltd.
