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Chemicals
[Tyr0]-C-Peptide (dog) CAS NO.101135-67-5
<p>[Tyr⁰]-C-Peptide (dog) is an N-terminally tyrosine-modified variant of the endogenous connecting peptide, specifically designed for enhanced immunodetection and metabolic research in canine models. Unlike standard C-peptide, this modification facilitates efficient radiolabeling (e.g., with ¹²⁵I) and improves antibody recognition, making it an indispensable tool for precise quantification of β-cell function. It is…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | [Tyr⁰]-C-Peptide (dog) |
| CAS NO. | 101135-67-5 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₄₆H₂₃₄N₃₈O₅₁ |
| Molecular Weight | 3527.9g/mol |
| Purity (RP-HPLC) | ≥95% |
| Solubility | Soluble in water or acidic aqueous solutions (e.g., 0.1% acetic acid); insoluble in organic solvents without denaturation |
| Endotoxin | ≤1 EU/mg (LAL test) |
| Biological Activity | Soluble in water or acidic aqueous solutions (e.g., 0.1% acetic acid); insoluble in organic solvents without denaturation |
| Storage Conditions | Store at –20°C, protected from light and moisture; avoid freeze-thaw cycles |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
The peptide functions as an equimolar byproduct of proinsulin processing, released alongside insulin from pancreatic β-cells. While it exhibits weak insulin-like signaling, its primary research utility lies in its metabolic stability—unlike insulin, it undergoes negligible hepatic extraction, allowing peripheral levels to accurately reflect pancreatic secretion rates. The Tyr⁰ modification does not alter this core pharmacokinetic profile but provides a chemical handle for tracer studies, enabling real-time tracking of C-peptide clearance and distribution in experimental settings.
2.PRODUCT INDICATIONS
This product is indicated for preclinical research focused on canine diabetes mellitus, β-cell mass assessment, and insulin resistance modeling. It serves as a critical standard for calibrating ELISA kits and radioimmunoassays (RIA) to monitor residual insulin secretion in diabetic dogs. Researchers in veterinary pharmacology and comparative medicine utilize it to evaluate islet transplantation outcomes, screen antidiabetic drugs, and validate diagnostic protocols for spontaneous canine diabetes.
3.CLINICAL EFFICACY OF PRODUCT
In experimental applications, [Tyr⁰]-C-Peptide (dog) demonstrates high diagnostic accuracy for quantifying endogenous insulin secretion, with linear detection ranges suitable for both basal and glucose-stimulated conditions. Studies confirm its reliability as a surrogate marker for β-cell function, showing strong correlation with insulinoma presence and treatment response in canine patients. Its Tyr⁰ modification significantly enhances assay sensitivity and specificity, reducing background interference in complex biological matrices like serum and plasma.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Tyr0CPeptideDog, #CanineCPeptide, #DogInsulin, #BetaCellFunction, #VeterinaryDiabetes, #MetabolismResearch, #ConnectingPeptide, #ResearchPeptide
If you have any product requirements, please send an email to:support@huanqiukeji9.com;whatsapp:85244969439
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Global Technology Co., Ltd.
