Chemicals

β-Endorphin, camel CAS NO.59887-17-1

<p>β-Endorphin, camel is a 31-amino acid endogenous neuropeptide derived from the proopiomelanocortin (POMC) precursor, representing the camelid-specific isoform of this classic opioid peptide. It is characterized by its high potency and broad physiological role, primarily functioning as a key modulator in the body&#39;s endogenous pain relief and stress response systems. This peptide is an essential research tool f…

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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Product information from the supplier.


TECHNICAL SPECIFICATIONS


Item
Specification
Product Name
β-Endorphin, camel  
CAS NO.
59887-17-1
Appearance
White to off-white lyophilized powder
Molecular Formula
C₁₅₅H₂₅₀N₄₂O₄₄S
Molecular Weight
3492.0g/mol
Purity (RP-HPLC)
≥98% 
Solubility

Soluble in 1M acetic acid, water, or dilute ammonia solution

Endotoxin
≤1 EU/mg 
Biological Activity
Potent full agonist at mu-opioid receptors (MOR)
Storage Conditions
Store at -20°C, protected from moisture and light
Stock Location
Stock in USA
MOQ
1g


1.MECHANISM OF ACTION

This peptide exerts its effects by acting as a potent agonist at μ-opioid receptors (MOR) and, to a lesser extent, δ- and κ-opioid receptors in the central nervous system and spinal cord. Upon binding to these G-protein coupled receptors, it inhibits adenylate cyclase activity, reduces intracellular cAMP levels, and modulates ion channel conductance, ultimately leading to the inhibition of neurotransmitter release (such as GABA and substance P). This mechanism effectively dampens pain signal transmission and alters emotional responses to stress, producing effects that are often compared to exogenous opiates but with a natural physiological context

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2.PRODUCT INDICATIONS

β-Endorphin, camel is indicated for in vitro and in vivo research applications focused on opioid receptor pharmacology, neurobiology, and immunology. It is widely used in studies investigating chronic pain models, stress-induced analgesia, addiction and reward pathways, as well as exercise-induced euphoria ("runner's high"). Additionally, due to its immunomodulatory properties, it serves as a valuable reagent for researchers exploring the connection between the nervous and immune systems, particularly in models of inflammation and immune cell function.

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3.CLINICAL EFFICACY OF PRODUCT

In experimental models, β-Endorphin demonstrates profound and long-lasting analgesic effects, with intracerebral administration shown to be significantly more potent than morphine in some paradigms. It effectively reduces pain-related behaviors in various nociceptive tests and modulates stress responses, exhibiting antidepressant-like effects in behavioral studies. Its efficacy extends beyond analgesia to include the regulation of immune cell proliferation and cytokine production, highlighting its multifaceted role in maintaining physiological homeostasis.

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4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.


Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.


We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards


Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

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5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

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Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.


We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.


Hot Tags: BetaEndorphin, #CamelBetaEndorphin, #EndogenousOpioid, #MuOpioidReceptor, #POMC, #AnalgesicPeptide, #Neuropeptide, #NeurobiologyResearch, #OpioidReceptorAgonist, #StressResponse

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