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Chemicals
ACTH (1-13), human CAS NO.22006-64-0
<p>ACTH (1-13), human is a synthetic peptide fragment corresponding to the N-terminal region of the adrenocorticotropic hormone, widely utilized in scientific research to study adrenal cortex stimulation and melanocortin receptor signaling. This fragment retains significant biological activity in vitro and in vivo models, making it an essential reagent for endocrinologists, neuroscientists, and pharmacologists inves…
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | ACTH (1-13), human |
| CAS NO. | 22006-64-0 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₇₅H₁₀₆N₂₀O₁₉S |
| Molecular Weight | ~1623.9 g/mol |
| Purity (RP-HPLC) | ≥98% |
| Solubility | Soluble in 1M acetic acid, DMSO, or deionized water |
| Endotoxin | ≤1 EU/mg |
| Biological Activity | Potent stimulator of adrenal cortisol secretion; activates melanocortin receptors (MC2R primarily) |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1g |
1.MECHANISM OF ACTION
This peptide exerts its effects primarily through high-affinity binding to the melanocortin type 2 receptor (MC2R) expressed on adrenal cortical cells, triggering a G-protein coupled signaling cascade that stimulates cholesterol desmolase activity and subsequent cortisol biosynthesis. Additionally, it may interact with other melanocortin receptors (MC1R, MC3R–MC5R) to modulate pigmentation, appetite, and inflammatory responses, depending on the tissue context and concentration used in experimental models.
2.PRODUCT INDICATIONS
Ideal for use in in vitro cell-based assays investigating adrenal steroidogenesis, in vivo rodent models of endocrine dysfunction, and receptor binding studies requiring a truncated, highly soluble ACTH analog. Suitable for academic laboratories, pharmaceutical R&D teams, and biotechnology companies focused on developing treatments for adrenal insufficiency, Cushing’s syndrome, and metabolic disorders linked to melanocortin pathways.
3.CLINICAL EFFICACY OF PRODUCT
While not intended for direct clinical use, ACTH (1-13), human serves as a critical research tool for evaluating the efficacy of melanocortin-targeted therapeutics in preclinical settings. Its ability to mimic key physiological functions of endogenous ACTH allows researchers to assess drug candidates for modulating cortisol production, reducing inflammation, or treating pigmentation disorders, thereby accelerating the translation of basic science into potential clinical applications.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: ACTH, #AdrenocorticotropicHormone, #MelanocortinReceptor, #CortisolStimulation, #PeptideResearch, #EndocrineResearch, #StressResponse, #PharmacologyTool, #Steroidogenesis, #ACTHFragment, #Neuroendocrinology, #ResearchPeptide
If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:85270846510
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Global Technology Co., Ltd.
