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Chemicals
Defensin HNP-2 (human) CAS NO.120721-97-3
<p>Defensin HNP-2 (human) is a cationic antimicrobial peptide predominantly found in human neutrophils, playing a vital role in the innate immune response against invading pathogens. This peptide exhibits high specificity for disrupting microbial membranes and is widely utilized in immunological and microbiological research to explore host defense mechanisms and inflammatory responses.</p>
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
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TECHNICAL SPECIFICATIONS
| Item | Specification |
|---|---|
| Product Name | Defensin HNP-2 (human) |
| CAS NO. | 120721-97-3 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₁₄₇H₂₁₇N₄₃O₃₇S₆ |
| Molecular Weight | 3370.95 g/mol |
| Purity (RP-HPLC) | ≥99.0% |
| Solubility | Soluble in 1M acetic acid, DMSO, or deionized water |
| Endotoxin | < 1 EU/mg |
| Biological Activity | Potent broad-spectrum antimicrobial activity; chemoattractant for immune cells |
| Storage Conditions | Store at -20°C, protected from light and moisture |
| Stock Location | Stock in USA |
| MOQ | 1kit |
1.MECHANISM OF ACTION
HNP-2 exerts its biological function by interacting with anionic components of microbial cell membranes, forming transmembrane pores that lead to the depolarization and subsequent lysis of bacterial cells. Additionally, it acts as a chemoattractant for monocytes and T lymphocytes, thereby bridging innate and adaptive immunity through specific receptor-mediated signaling pathways.
2.PRODUCT INDICATIONS
This product is indicated for researchers studying innate immunity, antimicrobial resistance, and inflammation. It is suitable for in vitro assays, cell culture studies, and animal models focused on infectious diseases and immune modulation, providing essential tools for developing novel therapeutic strategies against bacterial infections.
3.CLINICAL EFFICACY OF PRODUCT
While primarily a research reagent, the efficacy of HNP-2 has been demonstrated in preclinical studies for its ability to reduce bacterial load in infection models and modulate immune cell trafficking. Its high potency and specificity make it a valuable benchmark compound for evaluating new antimicrobial agents and understanding the pathophysiology of inflammatory disorders.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
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If you have any product requirements, please send an email to:business@huanqiukeji9.com;whatsapp:85270846510
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