Amylin (20-29) (human) CAS NO.118068-30-7

1.Mechanism of Action

Amylin (20-29) exerts its biological effects primarily through binding to specific receptors in the brain and peripheral tissues, notably the calcitonin receptor and the receptor activity-modifying proteins (RAMPs). It acts as an antagonist to insulin-stimulated glycogen synthesis in skeletal muscle and liver, slows gastric emptying via vagal afferent signaling, and reduces appetite by activating satiety centers in the hypothalamus. Its mechanism is complementary to insulin, helping to prevent postprandial hyperglycemia and promoting coordinated nutrient disposal.

2.Product Indications

This peptide is indicated for in vitro and in vivo research applications focused on diabetes mellitus, particularly type 1 and type 2, as well as for studies on islet cell physiology, metabolic syndrome, and appetite regulation. It is suitable for use in cell-based assays, animal models of obesity and diabetes, and pharmacokinetic studies investigating amylin analogs or receptor antagonists. Researchers in endocrinology, pharmacology, and metabolic disease modeling will find this peptide invaluable for elucidating amylin’s role in glucose control.

3.Clinical Efficacy of Product

While not approved for clinical use as a standalone therapeutic, Amylin (20-29) serves as a critical reference standard and mechanistic probe in preclinical research evaluating amylin-based therapeutics such as pramlintide. Studies using this peptide have demonstrated its ability to replicate key metabolic effects of native amylin, including reduced food intake, delayed gastric emptying, and improved glycemic control in diabetic models. Its consistent purity and activity make it a reliable tool for validating novel drug candidates targeting the amylin pathway.

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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