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Chemicals
Broxaldine CAS NO.3684-46-6
<div class="ybc-p">Broxaldine is a synthetic quinoline derivative specifically designed for its remarkable ability to suppress gastric acid secretion, making it an invaluable chemical probe for gastroenterological research and a promising lead compound for developing anti-ulcer drugs that target potassium channels in parietal cells.</div>
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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TECHNICAL SPECIFICATIONS
Item | Specification |
|---|---|
Product Name | Broxaldine |
CAS NO. | 3684-46-6 |
Appearance | Off-white to pale yellow crystalline powder |
Molecular Formula | C₁₇H₁₁Br₂NO₂ |
Molecular Weight | 421.08 g/mol |
Amino Acid Sequence | Not applicable |
Purity (RP-HPLC) | ≥98.0% |
Solubility | Soluble in DMSO and ethanol; insoluble in water |
Endotoxin | < 1 EU/mg |
Biological Activity | Exhibits potent and selective anti-secretory activity against chloride ions in the gastrointestinal tract; acts as a potassium channel blocker to inhibit gastric acid secretion |
Storage Conditions | Store at -20°C, protected from light and moisture |
Stock Location | USA / Germany / China (optional, based on actual stock) |
MOQ | 1 mg |
1.Mechanism of Action
Broxaldine exerts its primary pharmacological effect by selectively blocking specific potassium channels on the luminal membrane of gastric parietal cells, thereby inhibiting the apical potassium recycling necessary for the proton pump (H⁺/K⁺-ATPase) to function effectively, which ultimately leads to a marked reduction in hydrochloric acid secretion into the stomach lumen.
2.Product Indications
This specialized compound is primarily indicated for use in scientific research focused on understanding gastric physiology and acid secretion mechanisms, as well as for the development of novel therapeutic agents targeting peptic ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome in preclinical in vitro and in vivo studies.
3.Clinical Efficacy of Product
Although primarily used as a research chemical, preclinical data indicate that Broxaldine demonstrates high efficacy in significantly reducing basal and stimulated acid output in animal models, providing robust scientific evidence for its potential as a highly targeted mechanism-based treatment to alleviate acid-related gastrointestinal disorders without the broad systemic side effects associated with traditional proton pump inhibitors.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
HotTags:Broxaldine, #Gastroenterology, #AcidSecretion, #PotassiumChannel, #ResearchChemical, #Pharmaceutical, #AntiUler, #Preclinical, #CAS3684466, #DrugDiscovery
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