Bixin CAS NO.6983-79-5

TECHNICAL SPECIFICATIONS

1.Mechanism of Action

Bixin exerts its primary effects by directly quenching singlet oxygen and scavenging reactive oxygen species (ROS), thereby preventing oxidative damage to lipids, proteins, and DNA; it also upregulates the Nrf2/ARE signaling axis to boost endogenous antioxidant enzymes (SOD, CAT, GSH-Px) and suppresses NF‑κB‑driven pro‑inflammatory cytokines (TNF‑α, IL‑6). Additionally, bixin interferes with HMG‑CoA reductase activity and modulates PPAR‑α/γ expression, contributing to its cholesterol-lowering and insulin‑sensitizing actions.

2.Product Indications

This compound is indicated for in vitroand in vivoresearch on oxidative stress‑related pathologies such as atherosclerosis, non‑alcoholic fatty liver disease (NAFLD), UV‑induced skin damage, and neuroinflammation. It is also a key reference material for studies on natural colorants, carotenoid stability, and the chemopreventive potential of plant‑derived lipophilic antioxidants in cancer cell lines.

3.Clinical Efficacy of Product

Preclinical animal studies have shown bixin significantly reduces serum total cholesterol and LDL, attenuates diet‑induced hepatic steatosis, and protects against UVB‑induced cutaneous erythema and DNA damage. Though formal human clinical trials remain limited, its longstanding safety record as a widely consumed natural colorant combined with reproducible antioxidant and lipid‑modifying effects in rodent models supports its translational promise for nutraceutical and dermato‑cosmetic applications.

4.Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1.A rigorous quality management system

2.Batch traceability and stability data

3.Professional laboratory testing and validation

4.Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5.DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging

Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.

We can also customize packaging according to customer needs.

Shipping Methods 

Main Method: International Air Freight

We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

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