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Chemicals
Corticostatin I Rabbit CAS 134090736 China Factory Suppliers
High purity Corticostatin I rabbit CAS 134090-73-6 from a leading China factory. As premier suppliers, we provide this cationic 34-amino acid peptide for HPA axis and innate immune research, ideal for pharmaceutical R&D and biotechnology firms worldwide.
SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com
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About this product
Product information from the supplier.
Corticostatin I (rabbit), identified by CAS NO. 134090-73-6, is a premium research-grade peptide engineered for high-precision endocrinological and immunological studies. As a potent inhibitor of corticosterone release, this peptide specifically targets the adrenal glands, offering researchers a sophisticated tool to modulate the Hypothalamic-Pituitary-Adrenal (HPA) axis and explore the complex intersections of neuroendocrine regulation and innate immune defense.
Beyond its hormonal regulatory capacity, Corticostatin I exhibits significant antimicrobial and immunomodulatory properties. By disrupting microbial cell membranes and enhancing macrophage phagocytic activity, it serves as a vital reference in the study of defensins and the development of novel anti-inflammatory pathways. Manufactured under strict quality controls, our Corticostatin I ensures maximum purity and biological activity for consistent, reproducible results in in vitro laboratory research and preclinical drug discovery.
Detailed Parameters
| Product Name | Corticostatin I (rabbit) | CAS NO. | 134090-73-6 |
|---|---|---|---|
| Appearance | White to off-white lyophilized powder | Molecular Formula | C163H259N63O44S6 |
| Molecular Weight | 3997.64 g/mol | Purity (RP-HPLC) | ≥99.0% |
| Solubility | Water, dilute acetic acid, or PBS (pH 7.4) | Endotoxin | ≤0.5 EU/mg |
| Storage | -20°C, dry, dark, well-sealed | MOQ | 1 kit |
Key Advantages
High Purity Grade
Achieving ≥99.0% purity via RP-HPLC, ensuring minimal interference and high precision in biochemical assays.
Rapid Bio-Response
Potent inhibition of ACTH-stimulated steroidogenesis with an established ID50 of approximately 25 nM.
Dual Functionality
Unique capability to act as both a hormonal regulator and a potent antimicrobial agent against bacterial strains.
Specific Targeting
Competitive inhibition of ACTH receptors without affecting basal steroidogenesis or angiotensin II pathways.
Immune Modulation
Enhances macrophage phagocytic index and induces monocyte chemotaxis via L-type calcium channel stimulation.
Full Traceability
Every batch is accompanied by a COA, HPLC report, and MS chromatograms for complete quality validation.
Product Gallery
Management Platforms
GMP Production
Strict adherence to GMP-compliant synthesis systems for pharmaceutical-grade consistency.
Quality Control
Standardized processes from raw material procurement to final mass spectrometry testing.
Cold Chain Logistics
Secure -20°C shipping via DHL/FedEx to maintain peptide stability and biological activity.
Documentation Hub
Instant access to COA, purity reports, and third-party validation for all batches.
Scalable Supply
Flexible production capabilities ranging from gram-level research to ton-level industrial supply.
Regulatory Compliance
Compliance with FDA and international trade standards for seamless global distribution.
Investment Return Comparison
| Research Metric | Standard Peptides | GlobalTech Corticostatin I |
|---|---|---|
| Purity Level | <95% | ≥99.0% (RP-HPLC) |
| Binding Specificity | Low/Moderate | High (Competitive ACTH Inhibition) |
| Endotoxin Level | Variable | Ultra-Low (≤0.5 EU/mg) |
| Bio-Activity | Basic | Potent (ID50 ≈ 25 nM) |
| Documentation | Basic COA | COA + HPLC + MS + 3rd Party |
Frequently Asked Questions
Q: What is the primary application of Corticostatin I in pharmaceutical research?
It is primarily used as a reference peptide to evaluate the inhibition of ACTH-stimulated steroidogenesis in adrenal cell suspensions and to study the HPA axis regulation.
Q: How should Corticostatin I (rabbit) be stored to maintain its stability?
The product must be stored at -20°C in a dry, dark, and well-sealed container. It is critical to avoid repeated freeze-thaw cycles to prevent degradation.
Q: Is this peptide suitable for clinical use in humans?
No, this product is strictly designated for in vitro laboratory research, cell-based assays, and biochemical applications. It is not intended for clinical therapeutic use.
Q: What makes Corticostatin I different from other defensins?
Corticostatin I is the most potent member of its family, combining high specificity for the melanocortin system with broad-spectrum microbicidal activity.
Q: Which shipping methods are used for international delivery of these chemical APIs?
We utilize professional international air freight via DHL, FedEx, UPS, and TNT to ensure rapid transit and temperature-controlled stability.
Q: Can I request custom purity or packaging for bulk orders?
Yes, GlobalTech Co., Ltd. provides flexible customization for packaging and can accommodate diverse requirements from gram-level to ton-level production.
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