Cecropin A CAS 80451043 High Purity AMP Peptide China Suppliers Factory

Buy high-purity Cecropin A from leading China suppliers. Our factory provides research-grade cationic antimicrobial peptides with 98% purity for membrane biology and drug-resistant pathogen studies. Ideal for pharmaceutical R&D and biotechnology applications.

SupplierGlobal Technology Co., Ltd.www.hqtechtirz.com

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About this product

Product information from the supplier.

Cecropin A (CAS NO. 80451-04-3) is a high-purity antimicrobial peptide (AMP) engineered for advanced laboratory research and preclinical studies. Characterized by its potent broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, this cationic peptide utilizes a unique membrane-disruption mechanism to bypass traditional antibiotic resistance, making it an indispensable tool for researchers focusing on membrane biology and next-generation anti-infective agents.

Designed for rigorous scientific applications, Cecropin A exhibits significant efficacy in inducing apoptosis in various human cancer cell lines and modulating immune responses. With a purity level of ≥98.0% as verified by RP-HPLC, it serves as a critical reference standard for determining minimum inhibitory concentrations (MICs) and investigating the structure-activity relationships of amphipathic peptides in biotechnological and pharmaceutical settings.

Detailed Parameters

Product Name	Cecropin A	CAS NO.	80451-04-3
Appearance	White to off-white powder	Molecular Formula	C184H313N53O46
Molecular Weight	4003.84 g/mol	Purity (RP-HPLC)	≥98.0%
Solubility	Water, dilute acetic acid	Endotoxin	≤0.5 EU/mg
Storage	-20°C, dry, dark	MOQ	1g

Key Advantages

Anti-Resistance Mode

Utilizes physical membrane disruption (toroidal pores) rather than metabolic targeting, reducing the risk of microbial resistance.

Rapid Bactericidal Effect

Achieves fast osmotic lysis of target cells, demonstrating high efficacy against ESKAPE organisms and MDR isolates.

Multi-Functional Use

Beyond antimicrobial action, it shows promising anticancer properties and immunomodulatory functions in macrophage models.

Ultra-High Purity

Strict ≥98.0% RP-HPLC purity ensures reliable and reproducible results in sensitive biochemical assays.

Low Endotoxicity

Maintained at ≤0.5 EU/mg, ensuring minimal interference in cell-based assays and preclinical animal models.

Full Traceability

Each batch is accompanied by a comprehensive COA, MS chromatograms, and HPLC purity reports for total transparency.

Product Gallery

Management Platforms

GMP Compliant Systems

Production processes adhere to strict GMP standards for raw materials and synthesis.

Quality Control (QC)

Standardized validation covering purification, testing, and stability monitoring.

Batch Traceability

Rigorous documentation and stability data provided for every unique production lot.

Global Logistics

Specialized cold-chain shipping via DHL/FedEx to maintain peptide integrity.

Flexible Scaling

Capability to supply from milligram research levels up to ton-level industrial production.

Expert Collaboration

R&D partnerships with top universities to ensure cutting-edge peptide synthesis.

Investment Return Comparison

Metric	Traditional Antibiotics	Cecropin A (AMPs)
Resistance Risk	High (Enzyme-based)	Very Low (Physical)
Spectrum	Target-Specific	Broad Spectrum
Action Speed	Metabolic (Slower)	Membrane Lysis (Rapid)
Versatility	Anti-bacterial only	Antibacterial + Anticancer
Development Potential	Declining Efficiency	High Growth Potential

Frequently Asked Questions

Q: What is the primary application of Cecropin A in chemical drug manufacturing?

It is primarily used as a lead compound for antimicrobial discovery, a reference peptide for MIC assays, and in the study of membrane-active peptide interactions within pharmaceutical R&D.

Q: How does Cecropin A differ from conventional antibiotics?

Unlike conventional drugs that target specific enzymes, Cecropin A disrupts the bacterial cell membrane physically, creating pores that lead to osmotic lysis, which significantly hinders the development of resistance.

Q: What are the recommended storage conditions for this peptide?

Cecropin A should be stored at -20°C in a dry, dark, and well-sealed container. It is critical to avoid repeated freeze-thaw cycles to maintain biological activity.

Q: Can Cecropin A be used in clinical trials immediately?

No, this product is currently designated strictly for research use (RUO) and preclinical studies. It has not received regulatory approval for clinical therapeutic use.

Q: Which pathogens is Cecropin A most effective against?

It shows potent activity against a broad spectrum of pathogens, including E. coli, P. aeruginosa, A. baumannii, and S. aureus, with MICs typically between 1 to 3 μM.

Q: What quality documentation is provided with each order?

Each batch comes with a Certificate of Analysis (COA), an RP-HPLC purity report, and mass spectrometry (MS) chromatograms to ensure compliance with international standards.